Thanks to their ability to bind specifically a target substrate, specific peptides, also called GEPIs (read more), offer an interesting tool to detect both organic and inorganic compounds.
Specific peptides can be fused to a tag (e.g. fluorescent molecule) in order to be used to detect a target compound onto a surface or in a media.
As the binding is reversible, the peptides can be easily removed from the surface without damaging the bulk material.
Examples of developments:
GEPIs can be used to extract a contaminant or valuable compound from a specific media.
The peptides can then be grafted onto a support – e.g. beads, filters or surfaces – that will be used to extract them from the mix. Since the binding is reversible, the nanoparticle of interest or the contaminants can be fully recovered afterwards and the separation system can be reused.
Example of development: